M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease

Dwomoh L, Rossi M, Scarpa M, Khajehali E, Molloy C, Herzyk P, Bottrill AR, Sexton PM, Christopoulos A, Conn PJ, Lindsley CW, Bradley SJ, Tobin AB. M1 muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease. Sci Signal 15(760), 2022. https://doi.org/10.1126/scisignal.abm3720