Structure-activity studies reveal the molecular basis for GABAB receptor-mediated inhibition of high voltage-activated calcium channels by a-conotoxin Vc1.1

Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae H-S, O’Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB receptor-mediated inhibition of high voltage-activated calcium channels by a-conotoxin Vc1.1. ACS Chemical Biology 13(6): 1577-1587, 2018. https://doi.org/10.1021/acschembio.8b00190