Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into G protein selectivity

Mobbs J, Belousoff MJ, Harikumar K, Piper SJ, Xu X, Furness SGB, Venugopal H, Christopoulos A, Danev R, Wootten D, Thal DM, Miller LJ, Sexton PM. Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into G protein selectivity. PLoS Biol 19(6): e3001295: 2021. https://doi.org/10.1371/journal.pbio.3001295