The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism

Wootten D, Reynolds CA, Smith KJ, Mobarec JC, Koole C, Savage EE, Pabreja K, Simms J, Sridhar R, Furness SGB, Liu M, Thompson PE, Miller LJ, Christopoulos A, Sexton PM. The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism. Cell 165(7):1632-1643, 2016. https://doi.org/10.1016/j.cell.2016.05.023