The role of kinetic context in apparent biased agonism at GPCRs

Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR. The role of kinetic context in apparent biased agonism at GPCRs. Nat Commun 7:10842, 2016. https://doi.org/10.1038/ncomms10842