Centre Publications

Centre Publications

Role of conserved tyrosine lid residues in the activation of the M2 muscarinic acetylcholine receptor.

Node(s): Monash University
Published in: Molecular Pharmacology
Type: Research Paper

Pham V, Jansen MCCH, Thompson G, Heitman LH, Christopoulos A, Thal DM, Valant C. (2023). Molecular Pharmacology, 104 (3): 92-104. DOI: 10.1124/molpharm.122.000661.

Structural basis of promiscuous substrate transport in organic cation transporter 1.

Published in: Nature Communications
Type: Research Paper

Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O’Mara ML, Stewart AG. (2023). Nature Communications, 14:6374. doi: 10.1038/s41467-023-42086-9.

The effect of calcium removal from skim milk by ion exchange on the properties of the ultrafiltration retentate.

Node(s): University of Melbourne
Published in: Food Research International
Type: Research Paper

Wu Q, Ong L, Chen GQ, Varshney S, Hanssen E, Kentish SE, Gras SL (2023). Food Research International 173 (1): 113305. https://www.sciencedirect.com/science/article/pii/S0963996923008505

Molecular and structural insights into the 5-HT2C receptor as a therapeutic target for substance use disorders.

Node(s): Monash University
Published in: British Journal of Pharmacology
Type: Review

Ubhayarathna M, Langmead CJ, Diepenhorst NA, Stewart GD (2023). British Journal of Pharmacology Sept 7, online ahead of print. doi: 10.1111/bph.16233.

Development of matrix-embedded bovine tracheal organoids to study the innate immune response against bovine respiratory disease.

Node(s): University of Melbourne
Published in: Organoids
Type: Research Paper

Quah PS, Tran BM, Corbin VDA, Chang JJ-Y, Wong CY, Diaz-Méndez A, Hartley CA, Zeng W, Hanssen E, Trifunovic Z, Reading PC, Jackson DC, Vinca E, Coin LJM, Deliyannis G (2023). Organoids, 2(2): 82-101. https://doi.org/10.3390/organoids2020007

Cryo-EM structures of human arachidonate 12S-Lipoxygenase (12-LOX) bound to endogenous and exogenous inhibitors.

Node(s): Monash University The Walter and Eliza Hall Institute
Published in: Blood
Type: Research Paper

Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A (2023). Blood 142(14):1233-1242. doi: 10.1182/blood.2023020441. Commentary in Blood, October 5, 2023.

Half a century after their discovery: structural insights into exonuclease and annealase proteins.

Node(s): University of Wollongong
Published in: Engineering Microbiology
Type: Research Paper

Fitschen LJ, Newing TP, Johnston NP, Bell CE, Tolun G (2023). Engineering Microbiology, 100120, https://doi.org/10.1016/j.engmic.2023.100120

A STAT3 protein complex required for mitochondrial mRNA stability and cancer.

Node(s): Monash University
Published in: Cell Reports
Type: Research Paper

Fernando CD, Jayasekara WSN, Inampudi C, Kohonen-Corish MJR, Cooper WA, Beilharz TH, Josephs TM, Garama DFJ, Gough DJ (2023). Cell Reports 42(9):113033. Epub Sept 12, 2023. doi: 10.1016/j.celrep.2023.113033

Structural insight into selectivity of amylin and calcitonin receptor agonists. ,

Node(s): Monash University
Published in: Nature Chemical Biology
Type: Research Paper

Cao J, Belousoff MJ, Gerrard E, Danev R, Fletcher MM, Dal Maso E, Schreuder H, Lorenz K, Evers A, Tiwari G, Besenius M, Li Z, Johnson RM, Wootten D, Sexton PM (2023). Nature Chemical Biology, Aug 3, online ahead of print doi: 10.1038/s41589-023-01393-4. With industry partner Sanofi.

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR.

Node(s): Monash University
Published in: Nature Communications
Type: Research Paper

Burger WAC, Pham V, Vuckovic ZA, Powers AS, Mobbs JI, Laloudakis Y, Glukhova A, Wootten D, Tobin AB, Sexton PM, Paul SM, Felder CC, Danev R, Dror RO, Christopoulos A, Valant C, Thal DM (2023). Nature Communications 14(1): 5440. doi: 10.1038/s41467-023-41199-5. With industry collaborators, Karuna.